Active Ingredient: Sertraline
Definition
Sertraline is an antidepressant medication that belongs to the selective serotonin reuptake inhibitor (SSRI) class. It works by increasing the levels of serotonin, a neurotransmitter in the brain, which helps improve mood and reduce symptoms of depression and anxiety disorders
Indications for Use
Depression: Sertraline is used to treat major depressive disorder (MDD) in adults and adolescents aged 12 to 17 years
Anxiety Disorders: It is also indicated for the treatment of panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder (SAD), and premenstrual dysphoric disorder (PMDD)
Dosage
For depression and OCD in adults
Initial dose: 50 mg once daily, typically in the morning or evening
Maintenance dose: Range from 50 to 200 mg/day, adjusted based on individual response and tolerability
For other indications and in pediatric patients, the starting and maintenance doses may vary. It's important to follow the dosage prescribed by your healthcare provider
Drug Interactions
Sertraline can interact with several medications, including
Monoamine oxidase inhibitors (MAOIs)
Other SSRIs or SNRIs (serotonin-norepinephrine reuptake inhibitors)
Tricyclic antidepressants
Certain antipsychotic medications
Some antibiotics and antifungal drugs
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Side Effects
Common side effects may include nausea, diarrhea, insomnia, dizziness, dry mouth, and sexual dysfunction (e.g., decreased libido, difficulty achieving orgasm)
In some cases, sertraline can cause agitation, anxiety, and increased suicidal thoughts, especially in the early stages of treatment or when doses are adjusted
It's important to monitor for any unusual or severe side effects and report them to your healthcare provider promptly
As with any medication, it's crucial to take sertraline as prescribed and to discuss any concerns or potential interactions with your healthcare provider
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